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  1. Endothelial damage and activation may play central roles in the pathogenesis of systemic sclerosis (SSc) and are reflected by microparticles (MPs) and soluble selectins. The objective of this study was to dete...

    Authors: Line V. Iversen, Susanne Ullman, Ole Østergaard, Christoffer T. Nielsen, Poul Halberg, Tonny Karlsmark, Niels H.H. Heegaard and Søren Jacobsen
    Citation: BMC Musculoskeletal Disorders 2015 16:191
    Content type: Research article Published on:

  2. The assessment of mobility is important in the acute care setting. Existing tests suffer from limitations. The aim of the study was to examine the inter-rater reliability, the validity, the sensitivity to chan...

    Authors: Karin Pieber, Malvina Herceg, Tatjana Paternostro-Sluga, Eleonore Pablik, Michael Quittan, Peter Nicolakis, Veronika Fialka-Moser and Richard Crevenna
    Citation: BMC Musculoskeletal Disorders 2015 16:187
    Content type: Research article Published on:

  3. There are quite a few controversies on the surgical management of single-segment thoracic spinal tuberculosis with neurological deficits (STSTND). In this study, the clinical efficacy and feasibility of one-st...

    Authors: Hao Zeng, Penghui Zhang, Xiongjie Shen, Chengke Luo, Zhengquan Xu, Yupeng Zhang, Zheng Liu and Xiyang Wang
    Citation: BMC Musculoskeletal Disorders 2015 16:186
    Content type: Research article Published on:

  4. Exercise therapy following total hip replacement (THR) is considered to be important during the initial postoperative care, but till date only a few evidence-based recommendations exist. The aim of this survey...

    Authors: Christine Eulenburg, Anna-Lina Rahlf, Andrej Kutasow and Astrid Zech
    Citation: BMC Musculoskeletal Disorders 2015 16:185
    Content type: Research article Published on:

  5. Patellar tendinopathy identified by imaging modalities has been reported in asymptomatic athletes and associated with tendon-related symptoms. However there is little data in community-based populations. The a...

    Authors: Jason Toppi, Jessica Fairley, Flavia M. Cicuttini, Jill Cook, Susan R. Davis, Robin J. Bell, Fahad Hanna and Yuanyuan Wang
    Citation: BMC Musculoskeletal Disorders 2015 16:184
    Content type: Research article Published on:

  6. Vitamin D deficiency has been associated with a high number of health outcomes, and its role on the immune system has been deeply investigated in recent years, although poor data are still available on vitamin...

    Authors: Valentina Signori, Carlo L. Romanò, Elena De Vecchi, Roberto Mattina and Lorenzo Drago
    Citation: BMC Musculoskeletal Disorders 2015 16:183
    Content type: Research article Published on:

  7. The aim of this study was to evaluate, the existence of a signature of differentially expressed microRNAs (miRNAs) during osteogenic differentiation of bone marrow MSCs from OA and healthy donors and to descri...

    Authors: Pilar Tornero-Esteban, Luis Rodríguez-Rodríguez, Lydia Abásolo, María Tomé, Pedro López-Romero, Eva Herranz, Manuel A. González, Fernando Marco, Enrique Moro, Benjamín Fernández-Gutiérrez and José Ramón Lamas
    Citation: BMC Musculoskeletal Disorders 2015 16:182
    Content type: Research article Published on:

  9. Minimal invasive surgery (MIS) has gained growing popularity in total hip arthroplasty (THA) but concerns exist regarding component malpositioning. The aim of the present study was to evaluate femoral and acet...

    Authors: Moritz M. Innmann, Marcus R. Streit, Jeanette Kolb, Jochen Heiland, Dominik Parsch, Peter R. Aldinger, Matthias Königshausen, Tobias Gotterbarm and Christian Merle
    Citation: BMC Musculoskeletal Disorders 2015 16:180
    Content type: Research article Published on:

  10. Core myopathies are a clinically and genetically heterogeneous group of congenital myopathies with the common defined histopathological feature of focally reduced oxidative activity on muscle biopsy. It has a ...

    Authors: Rafael de Paiva Luciano, Eduardo Barros Puertas, Delio Eulalio Martins, Flavio Faloppa, David Del Curto, Luciano Miller Reis Rodrigues, Beny Schmidt, Acary Souza Bulle de Oliveira and Marcelo Wajchenberg
    Citation: BMC Musculoskeletal Disorders 2015 16:179
    Content type: Case report Published on:

  11. Osteoarthritis (OA) is likely to become an increasing burden in the coming decades. Various agents have been developed to slow the progression of OA, and are collectively known as ‘disease-modifying drugs’, ho...

    Authors: Kai Huang, Jia-peng Bao, Gavin James Jennings and Li-dong Wu
    Citation: BMC Musculoskeletal Disorders 2015 16:178
    Content type: Research article Published on:

  12. Unicondylar knee arthroplasty (UKA) is a well-established treatment for isolated osteoarthritis (OA) of the medial knee compartment. Aim of this retrospective study was to evaluate the early clinical and radio...

    Authors: Joel Baur, Lukas Zwicky, Michael Tobias Hirschmann, Thomas Ilchmann and Martin Clauss
    Citation: BMC Musculoskeletal Disorders 2015 16:177
    Content type: Research article Published on:

  13. The emergence of new therapies for the treatment of rheumatoid arthritis (RA), the paucity of head-to-head studies, and the heterogeneous nature of responses to current biologics highlight the need for the ide...

    Authors: Hubert G. Nüßlein, Rieke Alten, Mauro Galeazzi, Hanns-Martin Lorenz, Michael T. Nurmohamed, William G. Bensen, Gerd R. Burmester, Hans-Hartmut Peter, Karel Pavelka, Melanie Chartier, Coralie Poncet, Christiane Rauch and Manuela Le Bars
    Citation: BMC Musculoskeletal Disorders 2015 16:176
    Content type: Research article Published on:

  14. Fixation failure is a relatively common sequela of surgical management of proximal humerus fractures (PHF). The purpose of this study is to understand the current state of the literature with regard to the bio...

    Authors: David Cruickshank, Kelly A. Lefaivre, Herman Johal, Norma J. MacIntyre, Sheila A. Sprague, Taryn Scott, Pierre Guy, Peter A. Cripton, Michael McKee, Mohit Bhandari and Gerard P. Slobogean
    Citation: BMC Musculoskeletal Disorders 2015 16:175
    Content type: Research article Published on:

  15. The Timed Up and Go (TUG) test is quick and easy tests to assess patients’ functional mobility. However, its reliability in individuals with knee osteoarthritis (OA) has not been well established. The aims of ...

    Authors: Ahmad Alghadir, Shahnawaz Anwer and Jean-Michel Brismée
    Citation: BMC Musculoskeletal Disorders 2015 16:174
    Content type: Research article Published on:

  16. Retrieved metal-on-metal acetabular cups are valuable resources in investigating the wear behaviour of failed hip implants, but adequate methods to do so are lacking. To further contribute to addressing this i...

    Authors: Garima Govind, Johann Henckel, Harry Hothi, Shiraz Sabah, John Skinner and Alister Hart
    Citation: BMC Musculoskeletal Disorders 2015 16:173
    Content type: Technical advance Published on:

  17. The purpose was to investigate prevalence of bilateral discoid lateral menisci (DLM) in Han Chinese patients who received surgery for symptomatic DLM, as well as a follow-up study of their asymptomatic contral...

    Authors: Wen-Xin Liu, Jin-Zhong Zhao, Xiao-Qiao Huangfu, Yao-Hua He and Xing-Guang Yang
    Citation: BMC Musculoskeletal Disorders 2015 16:172
    Content type: Research article Published on:

  18. Acceptance and Commitment Therapy (ACT) for pain offers an alternative to traditional Cognitive Behavioural Therapy (CBT) approaches. ACT focuses on the enhancement of ‘psychological flexibility’ that enables ...

    Authors: Antonia Barke, Jenny Riecke, Winfried Rief and Julia A. Glombiewski
    Citation: BMC Musculoskeletal Disorders 2015 16:171
    Content type: Research article Published on:

  19. Adipose-derived stem cells (ASCs) are mesenchymal stem cells (MSCs) derived from adipose tissue. MSCs have multiple properties including anti-inflammatory and immunomodulatory effects in various disease models...

    Authors: Hyoju Yi, Kwi Young Kang, Youngkyun Kim, Hyerin Jung, Yeri Alice Rim, Narae Park, Juryun Kim, Seung Min Jung, Sung-Hwan Park and Ji Hyeon Ju
    Citation: BMC Musculoskeletal Disorders 2015 16:170
    Content type: Research article Published on:

  20. Single-photon emission computed tomography-computed tomography (SPECT-CT) is a highly sensitive tool for detecting bone metabolism. We determined whether subchondral bone metabolism, as indicated by SPECT-CT i...

    Authors: Du Hyun Ro, Ho-Young Lee, Chong Bum Chang and Seung-Baik Kang
    Citation: BMC Musculoskeletal Disorders 2015 16:169
    Content type: Research article Published on:

  21. A lack of data exists on the long-term magnetic resonance imaging (MRI) findings after surgical repair of tibial plateau fractures (TPFs). We evaluated the MRI findings 13 to 31 years after surgical repair of ...

    Authors: Georg Mattiassich, Ernst Foltin, Martin Pietsch, Oliver Djahani, Albert Kröpfl, Martin Fischmeister and Georg Scheurecker
    Citation: BMC Musculoskeletal Disorders 2015 16:168
    Content type: Research article Published on:

  22. Unstable pelvic fractures usually result from high-energy trauma. There are several treatment modalities available. The purpose of this study was to evaluate the clinical application of a new less invasive ili...

    Authors: Lei Zhu, Lu Wang, Di Shen, Tian-wen Ye, Liang-yu Zhao and Ai-min Chen
    Citation: BMC Musculoskeletal Disorders 2015 16:167
    Content type: Technical advance Published on:

  23. The advent of anti-tumor necrosis factor-α (TNFα) drugs has changed the course of ankylosing spondylitis (AS). While data are available concerning the long term effectiveness of single anti-TNF agents, little ...

    Authors: Mariagrazia Lorenzin, Augusta Ortolan, Paola Frallonardo, Francesca Oliviero, Leonardo Punzi and Roberta Ramonda
    Citation: BMC Musculoskeletal Disorders 2015 16:166
    Content type: Research article Published on:

  24. The clinical knowledge of factors related to the spread of pain on the body has increased and understanding these factors is essential for effective pain treatment. This population-based study examines local (...

    Authors: Anna Grimby-Ekman, Björn Gerdle, Jonas Björk and Britt Larsson
    Citation: BMC Musculoskeletal Disorders 2015 16:165
    Content type: Research article Published on:

  25. Glenohumeral instability is a common problem following traumatic anterior shoulder dislocation. Two major risk factors of recurrent instability are glenoid and Hill-Sachs bone loss. Higher failure rates of art...

    Authors: David J. Saliken, Troy D. Bornes, Martin J. Bouliane, David M. Sheps and Lauren A. Beaupre
    Citation: BMC Musculoskeletal Disorders 2015 16:164
    Content type: Research article Published on:

  26. Steroid associated osteonecrosis is difficult to treat. Teriparatide, as the only one bone anabolic drug, has achieved very promising effect in osteoporosis and other bone skeletal diseases. We carried out thi...

    Authors: Yulei Dong, Yulong Li, Cheng Huang, Kai Gao and Xisheng Weng
    Citation: BMC Musculoskeletal Disorders 2015 16:163
    Content type: Research article Published on:

  27. Percutaneous vertebroplasty (PVP) has been demonstrated to be effective in the treatment of osteoporotic fracture. The bilateral pedicular approach is the most frequently used method. However, unilateral PVP i...

    Authors: Haijun Li, Lei Yang, Jian Tang, Dawei Ge, Hao Xie, Jinhua Chen, Lipeng Yu, Haifeng Wei, Weizhong Tian, Tao Sui and Xiaojian Cao
    Citation: BMC Musculoskeletal Disorders 2015 16:162
    Content type: Research article Published on:

  28. The Short Musculoskeletal Function Assessment (SMFA) questionnaire is one of the most commonly used scales to evaluate functional status and quality of life (QOL) of patients with a broad range of musculoskele...

    Authors: Ying Wang, Zehui He, Lifang Lei, Dingkun Lin, Yajie Li, Gang Wang, Huimin Zhai, Jingli Xu, Guangqing Zhang and Meizhen Lin
    Citation: BMC Musculoskeletal Disorders 2015 16:161
    Content type: Research article Published on:

  29. The optimal treatment for proximal humeral fractures remains under debate. In this article, we report the mid-term results of patients who underwent the less-invasive implantation of a polyaxial locking plate ...

    Authors: Benjamin Bockmann, Benjamin Buecking, Daniel Franz, Ralph Zettl, Steffen Ruchholtz and Juliane Mohr
    Citation: BMC Musculoskeletal Disorders 2015 16:160
    Content type: Research article Published on:

  30. There is no consensus on the mechanisms by which anti-cyclic citrullinated peptide antibodies (anti-CCP) and rheumatoid factor (RF) influence the pathogenesis of rheumatoid arthritis (RA). The current study ve...

    Authors: Marcelo Bogliolo Piancastelli de Siqueira, Licia Maria Henrique da Mota, Shirley Claudino Pereira Couto and Maria Imaculada Muniz-Junqueira
    Citation: BMC Musculoskeletal Disorders 2015 16:159
    Content type: Research article Published on:

  31. Mechanical loading of bones activates modeling and suppresses remodeling by promoting bone formation. Eldecalcitol is approved for the treatment of osteoporosis in Japan and is often used in patients undergoin...

    Authors: Yusuke Yamasaki, Keita Nagira, Mari Osaki, Hideki Nagashima and Hiroshi Hagino
    Citation: BMC Musculoskeletal Disorders 2015 16:158
    Content type: Research article Published on:

  32. Direct measurement of disc biochemical content is impossible in vivo. Therefore, magnetic resonance imaging (MRI) is used to evaluate disc health. Unfortunately, current clinical imaging techniques do not adequat...

    Authors: Chun Chen, Zhiwei Jia, Zhihua Han, Tao Gu, Wei Li, Hao Li, Yong Tang, Jianhong Wu, Deli Wang, Qin He and Dike Ruan
    Citation: BMC Musculoskeletal Disorders 2015 16:157
    Content type: Research article Published on:

  33. Diffusion weighted imaging (DWI) and diffusion tensor imaging (DTI) are widely used in the evaluation of the central nervous system and recently have been reported as a potential tool for diagnosis of the peri...

    Authors: Ryo Miyagi, Toshinori Sakai, Eiko Yamabe and Hiroshi Yoshioka
    Citation: BMC Musculoskeletal Disorders 2015 16:156
    Content type: Research article Published on:

  34. The established scoring techniques based on radiographs present limitations in the evaluation of structural integrity due to high effectiveness of innovative therapeutic strategies. The aim of this study was t...

    Authors: Alexander Pfeil, Peter Oelzner, Diane M. Renz, Andreas Hansch, Gunter Wolf and Joachim Böttcher
    Citation: BMC Musculoskeletal Disorders 2015 16:155
    Content type: Research article Published on:

  35. Alpha-melanocyte-stimulating-hormone (α-MSH) has marked anti-inflammatory potential. Proinflammatory cytokines are critical mediators of the disturbed cartilage homeostasis in osteoarthritis, inhibiting anabol...

    Authors: Franco Capsoni, Anna Maria Ongari, Caterina Lonati, Riccardo Accetta, Stefano Gatti and Anna Catania
    Citation: BMC Musculoskeletal Disorders 2015 16:154
    Content type: Research article Published on:

  36. Platelet-rich plasma (PRP) preparations are a common treatment in osteoarthritis (OA) and inflammatory synovitis. However, there is ambiguity regarding the ideal concentration of leukocytes and platelets in th...

    Authors: Diana L. Ríos, Catalina López, María E. Álvarez, Ismael J. Samudio and Jorge U. Carmona
    Citation: BMC Musculoskeletal Disorders 2015 16:153
    Content type: Research article Published on:

  38. Despite the use of non-surgical methods to treat for the majority of midshaft fractures of the clavicle, it is remains controversial whether shortening of this bone following non-surgical treatment of a middle...

    Authors: Gustavo Santiago de Lima Figueiredo, Marcel Jun Sugawara Tamaoki, Bruno Dragone, Artur Yudi Utino, Nicola Archetti Netto, Marcelo Hide Matsumoto and Fábio Teruo Matsunaga
    Citation: BMC Musculoskeletal Disorders 2015 16:151
    Content type: Research article Published on:

  39. The component of the Quebec Task Force Classification System that subgroups patients based on the extent of their radiating pain and neurological signs has been demonstrated to have prognostic implications for...

    Authors: Hanne Rasmussen, Peter Kent, Per Kjaer and Alice Kongsted
    Citation: BMC Musculoskeletal Disorders 2015 16:150
    Content type: Research article Published on:

  40. The diagnostic golden standard for gout is to detect monosodium urate (MSU) crystals in synovial fluid. While some gout classification criteria include this variable, most gout diagnoses are based on clinical ...

    Authors: Mats Dehlin, Kalliopi Stasinopoulou and Lennart Jacobsson
    Citation: BMC Musculoskeletal Disorders 2015 16:149
    Content type: Research article Published on:

  41. The suture bridge (SB) technique and conventional double-row (DR) are both effective in repair of full-thickness rotator cuff tears . However, increasing numbers of scholars believe that the SB technique produ...

    Authors: Wenyong Fei and Weichun Guo
    Citation: BMC Musculoskeletal Disorders 2015 16:148
    Content type: Research article Published on:

  42. Low Back Pain (LBP) remains a common and costly problem. Psychological obstacles to recovery have been identified, but psychological and behavioural interventions have produced only moderate improvements. Revi...

    Authors: Tamar Pincus, Shamaila Anwar, Lance M. McCracken, Alison McGregor, Liz Graham, Michelle Collinson, John McBeth, Paul Watson, Stephen Morley, Juliet Henderson and Amanda J. Farrin
    Citation: BMC Musculoskeletal Disorders 2015 16:147
    Content type: Research article Published on:

  43. Asbestosis is characterized by lung and pleural fibrosis and by immune system dysregulation, with autoantibody production and systemic immune-mediated disease. No specific therapies are available for asbestosi...

    Authors: Laura Niccoli, Emanuele Cassarà, Olga Kaloudi, Carlotta Nannini, Micaela Romagnoli and Fabrizio Cantini
    Citation: BMC Musculoskeletal Disorders 2015 16:146
    Content type: Case report Published on:

  44. Percutaneous vertebroplasty (PVP) typically involves conventional lower-viscosity cement injection via bipedicular approach. Limited evidence is available comparing the clinical outcomes and complications in t...

    Authors: Liang Zhang, Zhongjun Liu, Jingcheng Wang, Xinmin Feng, Jiandong Yang, Yuping Tao and Shengfei Zhang
    Citation: BMC Musculoskeletal Disorders 2015 16:145
    Content type: Research article Published on:

  45. Tibial plateau fractures are a common intra-articular injury for which computed tomography (CT) scans are routinely used for preoperative planning. Three-dimensional reconstructions of CT scans have been incre...

    Authors: Andrew Dodd, Elizabeth Oddone Paolucci and Robert Korley
    Citation: BMC Musculoskeletal Disorders 2015 16:144
    Content type: Research article Published on:

  46. Generalised Joint Hypermobility (GJH) is suggested as an aetiological factor for knee injuries in adolescents and adults. It is presumed that GJH causes decreased joint stability, thereby increasing the risk o...

    Authors: Tina Junge, Lisbeth Runge Larsen, Birgit Juul-Kristensen and Niels Wedderkopp
    Citation: BMC Musculoskeletal Disorders 2015 16:143
    Content type: Research article Published on:

  47. Most bone tumors that occur in the clavicle are malignant. A few giant cell tumors (GCTs) of the clavicle have been reported; however, the most appropriate operative method for this tumor has never been discus...

    Authors: Satoshi Nagano, Toru Tsuchimochi, Masahiro Yokouchi, Takao Setoguchi, Hiromi Sasaki, Hirofumi Shimada, Shunsuke Nakamura, Yasuhiro Ishidou, Takuya Yamamoto and Setsuro Komiya
    Citation: BMC Musculoskeletal Disorders 2015 16:142
    Content type: Case report Published on:

  48. A localized non-surgical delivery of allogeneic human chondrocytes (hChonJ) with irradiated genetically modified chondrocytes (hChonJb#7) expressing transforming growth factor-β1 (TGF-β1) showed efficacy in re...

    Authors: Hyun Joo Yoon, Suk Bum Kim, Dhara Somaiya, Moon Jong Noh, Kyoung-Baek Choi, Chae-Lyul Lim, Hyeon-Youl Lee, Yeon-Ju Lee, Youngsuk Yi and Kwan Hee Lee
    Citation: BMC Musculoskeletal Disorders 2015 16:141
    Content type: Research article Published on:

  49. Fibular allograft with impaction bone grafting (FAIBG) is an effective hip-preservation method for avoiding total hip arthroplasty in the early stage of femoral head necrosis. However, whether thorough debride...

    Authors: Guangquan Zhou, Ying Zhang, Linghong Zeng, Wei He, Zhihui Pang, Xiumin Chen, Yujing Xu, Liao Shaoyi Stephen and LeiLei Chen
    Citation: BMC Musculoskeletal Disorders 2015 16:140
    Content type: Research article Published on:
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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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