S-Adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: A double-blind cross-over trial. [ISRCTN36233495]

Table 4 Pain scores (pain was scored on a visual analog scale where 0 = no pain and 100 = the highest possible pain level).

		Baseline		SAMe		Celecoxib
Variable	N+	Mean	(SD)	Mean	(SD)	Mean	(SD)	Stdif
Pain Level Today
Month 1	52	45.3	(23.8)	33.8*	(24.0)	24.6*	(23.9)	-0.33*
Month 2	52	46.1	(24.2)	24.0*	(19.5)	24.4*	(23.6)	0.01
Pain Level over the Past Month
Month 1	52	56.7	(22.5)	44.1*	(22.4)	32.5*	(24.0)	-0.42**
Month 2	52	57.0	(23.4)	34.7*	(22.7)	33.1*	(22.8)	-0.05

Stdif: Standardized difference scores – positive numbers indicate a better response with SAMe. +Sample size is less than 57 due to missing data in either Phase 1 or Phase 2. *Difference between baseline and treatment is statistically significant (p < 0.05). ** Difference between SAMe and Celecoxib is statistically significant (p < 0.05).

ISSN: 1471-2474