Table 1 Participant characteristics
Mean (SD) n = 153 | ||
|---|---|---|
Gender | 48 % female | |
Age (years) | 62.2 (7.0) | |
BMI (kg/m2) | 27.8 (4.7) | |
Any radiographic OA (%) | 56.0 | |
Osteophyte, any site (%) | 9.2 | |
Medial JSW (mm) | 4.73 (0.97) | |
Lateral JSW (mm) | 6.76 (1.37) | |
JSN scores (OARSI grade) (%) | ||
Medial | 0 | 49.7 |
1 | 41.2 | |
2 | 8.5 | |
3 | 0.7 | |
Lateral | 0 | 83.7 |
1 | 13.1 | |
2 | 2.0 | |
3 | 1.3 | |
Annual change in joint space width: | ||
Medial (mm) | −0.05 (0.16) | |
Medial (%) | −1.2 (3.9) | |
Lateral (mm) | −0.12 (0.24) | |
Lateral (%) | −1.8 (3.9) | |
Medial cartilage volume (tibia + femur, μL) | 6296 (1523) | |
Lateral cartilage volume (tibia + femur, μL) | 7080 (1671) | |
Annual change in cartilage volume: | ||
Medial (μL) | −134 (202) | |
Medial (%) | −2.1 (3.0) | |
Lateral (μL) | −106 (165) | |
Lateral (%) | −1.6 (2.5) | |
Meniscal extrusions | ||
Medial – present at baseline (%) | 16.3 | |
Medial – worsening extrusion (%) | 9.2 | |
Lateral – present at baseline (%) | 2.0 | |
Lateral – worsening extrusion (%) | 0.7 | |
Meniscal tears | ||
Medial – present at baseline (%) | 98.0 | |
Medial – worsening tear (%) | 10.5 | |
Lateral – present at baseline (%) | 96.7 | |
Lateral – worsening tear (%) | 15.0 | |
Cartilage defects | ||
Medial - present at baseline (%) | 23.5 | |
Medial - worsening (%) | 37.7 | |
Lateral - present at baseline (%) | 21.6 | |
Lateral - worsening (%) | 36.4 | |
Cartilage thickness (average, tibia & femur) | (n = 67) | |
Medial (mm) | 3.07 (0.41) | |
Lateral (mm) | 3.33 (0.41) | |
Annual change in cartilage thickness | ||
Medial (mm) | −0.17 (0.27) | |
Medial (%) | −6.04 (8.45) | |
Lateral (mm) | −0.26 (0.3) | |
Lateral (%) | −8.12 (8.69) | |