Table 2 Summary of different genetic model comparison results
SNP | Genetic model | OR (95 % CI) | Z | P value | I2% | P het | Effect model | Egger’s test | |
|---|---|---|---|---|---|---|---|---|---|
t value | P value | ||||||||
rs111090870 | TT + TC vs. CC | 1.12 (1.09–1.15) | 7.66 | 0.000 | 68.8 | <0.001 | R | 0.42 | 0.684 |
TT vs. TC + CC | 1.42 (1.36–1.49) | 15.49 | 0.000 | 42.6 | 0.058 | F | 0.92 | 0.378 | |
TT vs. CC | 1.36 (1.27–1.45) | 9.07 | 0.000 | 73.2 | <0.001 | R | 0.98 | 0.349 | |
TC vs. CC | 1.13 (1.09–1.18) | 5.92 | 0.000 | 56.3 | 0.009 | R | −0.07 | 0.949 | |
T vs. C | 1.21 (1.16–1.26) | 9.52 | 0.000 | 68.7 | <0.001 | R | 0.55 | 0.597 | |
rs678741 | GG + GA vs. AA | 0.79 (0.77–9.82) | 16.79 | 0.000 | 0.0 | 0.998 | F | 0.85 | 0.458 |
GG vs. GA + AA | 0.69 (0.64–0.74) | 10.98 | 0.000 | 0.0 | 0.880 | F | −0.82 | 0.470 | |
GG vs. AA | 0.68 (0.65–0.72) | 13.22 | 0.000 | 0.0 | 0.517 | F | −1.09 | 0.356 | |
GA vs. AA | 0.88 (0.85–0.91) | 8.12 | 0.000 | 0.0 | 0.904 | F | −0.73 | 0.519 | |
G vs. A | 0.83 (0.81–0.85) | 13.75 | 0.000 | 0.0 | 0.743 | F | −0.69 | 0.542 | |
rs11598564 | GG + GA vs. AA | 1.13 (1.10–1.16) | 7.98 | 0.000 | 0.0 | 0.649 | F | 0.32 | 0.769 |
GG vs. GA + AA | 1.09 (0.84–1.43) | 0.64 | 0.519 | 88.8 | <0.001 | R | 0.29 | 0.726 | |
GG vs. AA | 1.12 (1.33–1.52) | 10.12 | 0.000 | 0.0 | 0.761 | F | −0.71 | 0.526 | |
GA vs. AA | 1.13 (1.08–1.18) | 5.34 | 0.000 | 0.0 | 0.739 | F | 1.02 | 0.384 | |
G vs. A | 1.21 (1.16–1.25) | 10.03 | 0.000 | 22.2 | 0.273 | F | 0.66 | 0.557 | |
rs625039 | GG + GA vs. AA | 1.07 (1.05–1.09) | 7.45 | 0.000 | 0.0 | 0.648 | F | 0.20 | 0.850 |
GG vs. GA + AA | 1.30 (1.23–1.37) | 9.05 | 0.000 | 0.0 | 0.509 | F | 1.18 | 0.303 | |
GG vs. AA | 1.17 (1.13–1.21) | 9.48 | 0.000 | 0.0 | 0.651 | F | 0.66 | 0.545 | |
GA vs. AA | 1.09 (1.05–1.12) | 4.66 | 0.000 | 0.0 | 0.573 | F | −0.35 | 0.747 | |
G vs. A | 1.14 (1.11–1.17) | 10.14 | 0.000 | 0.0 | 0.584 | F | 1.10 | 0.333 | |