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Table 3 Results from 5 Studies Investigating H. pylori

From: Determining the association between fibromyalgia, the gut microbiome and its biomarkers: A systematic review

Author (Year)

Cohort

Material H. pylori marker

H. pylori positive (%)

FMS

Controls

p- value

Goebel (2008) [19]

33 FMS

17 CRPS

57 HC

Serum antibodies

IgA or IgG

33.0

HC: NT CRPS: 47.0

n.s.

Akkaya (2011) [20]

65 FMS

41 HC

Serum antibodies

IgA

IgG

30.8

67.7

17.1

43.9

0.169

0.025

Olama (2013) [21]

100 FMS

100 HC

Serum antibodies

IgA

IgG

50.0

68.0

24.0

32.0

<  0.001

< 0.001

Rodrigo (2013) [22]

104 FMS

125 IBS

Gastroduodenal biopsyH&E + Giemsa staining, polyclonal anti-H. pylori antibody, microbial cultures

42.0

46.0

n.s.

Gezici (2014) [23]

41# FMS

Gastric biopsy

Culture

78.0

–

–

  1. Key: # all had dyspepsia; FMS fibromyalgia; HC healthy controls; CRPS chronic regional pain syndrome; IBS irritable bowel syndrome; NT not tested; NA not reported; n.s. not statistically significant.