Based on the proposed criteria, PJI is defined as follows | |
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(1) Presence of fistula communicating to the prosthesis; or | |
(2) The same microorganism isolated by culture in at least two separate tissue or fluid samples obtained from the affected joint or prosthesis; or | |
(3) Four of the following six criteria: | |
(a) Elevation of erythrocyte sedimentation rate (ESR) and serum C-reactive protein (CRP) concentration, | |
(b) Elevation of the leukocyte count in the synovial fluid, | |
(c) Elevation of the percentage of neutrophils, | |
(d) Presence of purulence in the affected joint, | |
(e) Isolation of only one microorganism in a culture of the tissue or periprosthetic fluid, or | |
(f) More than five neutrophils per high power field in at least five high power fields observed from the histological analysis of the periprosthetic tissue at 9400X magnification. |