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Table 1 Criteria for PJI

From: Bacteria drug resistance profile affects knee and hip periprosthetic joint infection outcome with debridement, antibiotics and implant retention

Based on the proposed criteria, PJI is defined as follows

(1) Presence of fistula communicating to the prosthesis; or

(2) The same microorganism isolated by culture in at least two separate tissue or fluid samples obtained from the affected joint or prosthesis; or

(3) Four of the following six criteria:

 (a) Elevation of erythrocyte sedimentation rate (ESR) and serum C-reactive protein (CRP) concentration,

 (b) Elevation of the leukocyte count in the synovial fluid,

 (c) Elevation of the percentage of neutrophils,

 (d) Presence of purulence in the affected joint,

 (e) Isolation of only one microorganism in a culture of the tissue or periprosthetic fluid, or

 (f) More than five neutrophils per high power field in at least five high power fields observed from the histological analysis of the periprosthetic tissue at 9400X magnification.