Table 1 Patient demographics and clinical characteristics (n = 114)

Demographic/clinical variables	Number of patients (%)^a
Age (years) at diagnosis	N = 108^b
Mean (SD)	55.5 (13.9)
Gender
Female	85 (75)
DAS28 score closest to enrolment
< 2.6	0 (0)
2.6 < 3.2	0 (0)
3.2 ≤ 5.1	114 (100)
> 5.1	0 (0)
Mean (SD)	3.8 (0.5)
Number of swollen joints closest to enrolment	N = 111
0–1	57 (51)
2–4	43 (39)
≥5	11 (10)
Median (IQR)	1.0 (1.0–3.0)
Number of tender joints closest to enrolment	N = 111
0–1	21 (19)
2–4	56 (50)
≥5	34 (31)
Median (IQR)	3.0 (2.0–5.0)
Number of comorbidities at enrolment
0	17 (15)
1	33 (29)
2	39 (34)
3	11 (10)
4	11 (10)
≥ 5	3 (3)
Median (IQR)	2.0 (1.0–2.0)
Number of cDMARDs received between RA diagnosis and start of observation period^c
None recorded	1 (1)
1	25 (22)
2	56 (49)
3	28 (25)
4	3 (3)
≥ 5	1 (1)
Mean (SD)	2.1 (0.8)

cDMARDs Conventional disease-modifying anti-rheumatic drugs, DAS Disease activity score, IQR Interquartile range, RA Rheumatoid arthritis, SD Standard deviation
^aResults reported as n (%) unless otherwise indicated (e.g. mean, median)
^bSix patients did not have a date of diagnosis recorded
^cStart of observation period is 24 months prior to enrolment

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