Fig. 4From: Anti-IL17 antibody Secukinumab therapy is associated with ossification in giant cell tumor of bone: a case report of pathologic similarities and therapeutic potential similar to DenosumabComparative gene expression of three cases of GCTB with different treatment modalities. TRAP, Cathepsin K, RANKL, and MMP9 represent osteoclast markers and function. Osteoprotegerin is a marker for osteoblast/bone formationBack to article page