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Table 1 Baseline characteristics of the three groups

From: Dose tranexamic acid reduce blood loss associated with simultaneous bilateral distal tibial tubercle-high tibial osteotomy?

Variable

single-dose

two-dose

multiple-dose

P value (between group)

Patient characteristics

 Age (yr)

54.63 ± 6.71

57.81 ± 5.53

55.15 ± 6.17

0.250a

 Gender(male/female)

6/12

5/13

8/10

0.566b

 BMI

25.73 ± 2.41

26.92 ± 2.54

26.56 ± 1.94

0.166a

Medical history

 Diabetes

1

1

1

0.864b

 Hypertension

3

1

2

 Arrhythmia

1

2

2

ASA score

 I

10

11

13

0.842b

 II

6

6

4

 III

2

1

1

Preoperative blood tests

 Hb (g/L)

132.13 ± 11.01

129.32 ± 9.23

131.15 ± 10.33

0.714a

 Hct (%)

40.16 ± 3.14

38.33 ± 2.75

39.14 ± 2.16

0.138 a

 D-dimer (mg/L)

0.23 ± 0.10

0.25 ± 0.10

0.17 ± 0.10

0.053 a

 FDP (mg/L)

2.66 ± 0.61

2.43 ± 0.59

2.58 ± 0.42

0.446a

 LKS scoers

43.15 ± 7.76

42.60 ± 6.95

44.20 ± 7.27

0.802 a

 VAS scoers

5.12 ± 1.65

5.43 ± 1.14

5.38 ± 1.32

0.773 a

QoL of SF-12

 PCS

32.62 ± 3.45

33.14 ± 4.16

32.73 ± 4.35

0.919 a

 MCS

49.73 ± 6.95

47.56 ± 6.18

50.14 ± 7.27

0.480 a

  1. Abbreviations: ANOVA analysis of variance, BMI body mass index, ASA American Society of Anesthesiologists, Hb haemoglobin, Hct haematocrit, FDP fibrinogen degradation products, QoL quality of life, SF-12 12-item Short Form Health Survey, PCS physical component summary scores, MCS mental component summary scores
  2. Intergroup comparisons performed using ANOVA or Chi-square test (aANOVA; bChi-square test)