Variable | single-dose | two-dose | multiple-dose | P value (between group) |
---|---|---|---|---|
Thromboembolic events | ||||
DVT | 1 | 0 | 1 | 0.595 |
PE | 0 | 0 | 0 | – |
Incision-related complications | ||||
Dehiscence | 0 | 0 | 0 | – |
Hematoma | 1 | 1 | 0 | 0.595 |
Edge necrosis | 0 | 0 | 0 | – |
Infection | 0 | 0 | 0 | – |
TXA adverse reactions | ||||
Dizziness or headache | 1 | 1 | 2 | 0.763 |
Nausea and Vomiting | 1 | 2 | 2 | 0.802 |
Rash | 0 | 0 | 1 | 0.361 |