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Table 3 Key results from the base-case analysis (Discounted, undiscounted)

From: Cost-consequence analysis of continuous denosumab therapy for osteoporosis treatment in South Korea

Variables

Discounted

Undiscounted

Dmab-C

Dmab-D

Difference

Dmab-C

Dmab-D

Difference

Total fracturea

54.01

100.65

-46.64

98.55

179.88

-81.33

 Vertebral fracture

13.89

48.09

-34.21

25.01

84.49

-59.48

 Non-vertebral fracture

40.13

52.56

-12.43

73.54

95.38

-21.85

Fracture-related deatha

1.76

3.06

-1.29

5.77

9.82

-4.04

Total lifetime costsb

4,017,571

5,372,225

-1,354,655

6,432,703

8,796,976

-2,364,273

 Continuous drug costb

717,120

0

717,120

754,004

0

754,004

 Subsequent drug costb

1,846,137

2,654,788

-808,651

3,025,230

3,940,990

-915,760

 Fracture treatment costb

1,454,314

2,717,437

-1,263,124

2,653,470

4,855,986

-2,202,517

  1. Dmab-C: continuous denosumab therapy; Dmab-D: denosumab discontinuation (discontinuation of denosumab when the T-score improved from below − 2.5 to -2.5 < T-score≤-2.0 after denosumab treatment); aper lifetime in 100 patients; bper patient, KRW