Factor investigated | Sample | Studies | Design | Limitations | Inconsistency | Indirectness | Imprecision | Publication bias | Absolute effect (95% CI) | Quality |
---|---|---|---|---|---|---|---|---|---|---|
Patient related factors | 227 | 3 | 1 RCT 2 R Cohorta | Serious limitationsc | No inconsistency | Serious Indirectnesse | Serious imprecisionf | Undetected | Due to heterogeneity of study design, outcome measures and factors investigated meta-analysis was not possible | Low ⨂ ⨂ ◯ ◯ |
Image guidance | 95 | 2 | 2 RCT | Serious limitationsc | Inconsistencyd | Serious Indirectnesse | Serious imprecisionf | Undetected | Very low ⨂ ◯ ◯ ◯ | |
Injection location | 270 | 3 | 1 RCT 2 R Cohorta | Serious limitationsc | Inconsistencyd | Serious Indirectnesse | Serious imprecisionf | Undetected | Very low ⨂ ◯ ◯ ◯ | |
USS findings | 264 | 2 | 1 R Cohorta 1 P Cohortb | Serious limitationsc | No inconsistency | Serious Indirectnesse | Serious imprecisionf | Undetected | Low ⨂ ⨂ ◯ ◯ |