Skip to main content

Table 1 Clinical data of 22 cases with bone metastasis from follicular thyroid carcinoma

From: Complete resorption of the humerus in metastatic thyroid carcinoma: a case report

Authors

Year

Age

(year)

Sex

Symptom of metastasis

Location of metastasis

Surgery on primary site

Treatments of bone metastasis

Outcomes

Akdemir et al. [9]

2005

57

M

Headache and a mass in the right occipitoparietal region

Skull

Total thyroidectomy

Metastasectomy,

radiotherapy

No recurrence for 12 months

Araki et al. [10]

2008

55

F

The feeling of constant discoordination after tooth extraction and gingival swelling

Mandible

Total thyroidectomy

Mastectomy,

radiotherapy

Not available

Matsuno et al. [8]

Present Case 1

2010

58

F

Hearing disturbance and swelling of the right maxilla

Skull base

Left thyroidectomy

Metastasectomy, 131I

therapy and thyroid

hormone

No recurrence for 12 months

Present Case 2

 

71

F

Hoarseness

Skull base

Right thyroidectomy

Metastasectomy, 131I

therapy and thyroid

hormone

No recurrence for 12 months

Sandu et al. [11]

2011

50

F

Progressive spinal cord compression

Vertebra

Total thyroidectomy

Metastasectomy, bone cement plaster, posterior arthrodesis and 131I therapy

No recurrence for 36 months

Tahamtan et al. [12]

2012

42

F

Frontal scalp subcutaneous nodule

Skull

Total thyroidectomy

Reconstruction of bone defect

Not available

Koppad et al. [13]

2012

48

F

Swelling in the frontal region of the skull

Massive

skull

No intervention

Supraphysiological,

dose of thyroxine

Not available

Coban et al. [14]

2014

63

F

Bowel and bladder incontinence

Vertebra

Total thyroidectomy

131I therapy

Not available

C et al. [15]

2014

76

M

Painless swelling in the left side body of the mandible

Mandible

Not

available

Not available

Not available

De Pasquale et

al [16].

2014

65

F

A large painful mass developed on the left inferior part of her face

Mandible

Total thyroidectomy

Metastasectomy, 131I therapy, prosthetic bone reconstruction

No

recurrence for 46 months

Zhang et al. [17]

2014

65

F

Progressive swelling

of her neck

Cervical

vertebra

Total thyroidectomy

Metastasectomy, internal fixation, 131I therapy, and thyroid hormone

No recurrence for 15 months

Mizoshiri et al. [18]

2015

68

F

Left hip joint pain

Femoral head; right rib

Partial thyroidectomy

Bipolar hip arthroplasty, metastasectomy

No recurrence for 18 months

Bansal et al. [19]

2016

55

F

Progressively increasing swelling on the scalp

Skull

Total thyroidectomy

No intervention

No recurrence for 6 months

Baião et al. [20]

2017

84

F

Acute paraparesis

Vertebra

Total thyroidectomy

131I therapy and thyroid

hormone

No recurrence for 6 months

Akgedik et al. [21]

2017

51

M

Pleuritic pain

Rib

Total thyroidectomy

Metastasectomy, 131I therapy, and thyroid hormone

No recurrence for 12 months

Yang et al. [30]

2017

38

M

Pathological fracture of the humerus

Humerus

Total thyroidectomy

Metastasectomy, replacement of left proximal

humerus, and 131I therapy

Not available

Karimifar et al. [22]

2018

52

M

Hip fracture and hypercalcemia

Hip and vertebra

Total thyroidectomy

Metastasectomy, internal fixation, 131I therapy, and

thyroid hormone

Not available

Liu et al. [23]

2021

65

F

Numbness in right hand, weakness in right lower limbs

Skull

Not

available

Metastasectomy

Not available

Omar et al. [24]

2022

74

F

Sacral pain

Sacral

region

Right thyroidectomy

Decompressive surgery, 131I therapy, and thyroid hormone

Not available

Yang et al. [25]

2022

57

F

Progressive dysphagia, hoarse voice, weakness of her right shoulder, and a goiter.

Skull base

Total thyroidectomy

Radiotherapy,

chemotherapy

Not available

Chen et al. [26]

2022

67

F

Vertebral pain

Vertebra

Total thyroidectomy

Artificial vertebral body replacement, 131I therapy, and thyroid hormone

No recurrence for 12 months

Fataftah et al. [27]

2022

60

F

Knee pain and limping

Knee

Total thyroidectomy

Total knee replacement, 131I therapy

No recurrence for 12 months