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Table 3 Cost-effectiveness analysis results (main analysis)

From: Cost-effectiveness of Transforaminal epidural steroid injections for patients with ACUTE sciatica: a randomized controlled trial

Outcome

Sample size Outcome

∆C (95%CI)

∆E (95%CI)

ICER

Distribution CE-plane (%)

Comparison 1

(Int. group 1 (Usual care + TESI) vs. Control (Usual care))

 

Int. Group 1

Control

€

Points

€/point

NE

SE

SW

NW

QALYs (0–1)1

46

45

1839 (− 2891 to 6281)

0.008 (− 0.41 to 0.57)

234,478

44.5

17.1

8.1

30.3

Back pain (0–10) 2

46

45

1694 (− 3037 to 6177)

0.6 (− 0.5 to 1.7)

2742

11.4

3.7

23.2

61.7

Leg pain (0–10) 3

46

45

1730 (− 2886 to 6247)

−0.4 (− 2.2 to 1.4)

− 4409

54.4

16.5

10.2

19.0

Functioning (0–23) 4

46

45

1746 (− 3029 to 6240)

1.5 (− 1.7 to 4.7)

1158

12.0

5.1

21.5

61.4

Global Perceived Effect 5

46

45

1662 (− 2903 to 6156)

0.04 (−0.02 to 0.11)

39,295

71.5

23.5

0.4

4.6

Comparison 2

(Int. group 1 (Usual care + TESI) vs. Int. group 2 (Usual care + TEI))

 

Int. Group 1

Int. Group 2

€

Points

€/point

NE

SE

SW

NW

QALYs (0–1)1

46

50

1692 (− 3245 to 6146)

−0.011 (−0.061 to 0.038)

− 150,243

20.5

11.0

15.9

52.6

Back pain (0–10) 2

46

50

1616 (− 3303 to 6113)

−0.01 (− 1.3 to 1.3)

− 12,3742

37.9

16.1

11.5

34.5

Leg pain (0–10) 3

46

50

1644 (− 3280 to 6062)

−0.1 (−1.5 to 1.3)

− 25,791

40.3

15.5

11.7

32.5

Functioning (0–23) 4

46

50

1644 (− 3463 to 6167)

0.99 (−2.15 to 4.12)

1664

18.6

6.8

20.4

54.2

Global Perceived Effect 56

46

50

–

–

–

–

–

–

–

Comparison 3

(Int. group 2 (Usual care + TEI) vs. Control (Usual care)

 

Int. Group 2

Control

€

 Points

€/point

NE

SE

SW

NW

QALYs (0–1)1

50

45

735 (− 3815 to 5734)

0.012 (−0.040 to 0.064)

59,442

41.9

26.0

12.3

19.9

Back pain (0–10) 2

50

45

802 (− 3895 to 5824)

0.8 (−0.4 to 1.9)

1033

7.4

4.1

32.5

56.0

Leg pain (0–10) 3

50

45

770 (− 3893 to 5641)

−0.2 (−1.7 to 1.4)

− 4136

42.4

21.3

15.2

21.0

Functioning (0–23) 4

50

45

772 (− 3778 to 5627)

0.4 (−3.3 to 4.0)

2135

27.0

14.6

22.7

35.7

Global Perceived Effect 5

50

45

747 (− 3863 to 5627)

0.05 (−0.01 to 0.10)

16,564

67.9

32.1

0.0

0.0

  1. Usual care Oral medication: TESI Transforaminal Epidural Steroid Injection: TEI Transforaminal Epidural Injection
  2. C Costs: E Effects: ICER Incremental Cost-Effectiveness Ratio: CE-plane Cost-Effectiveness plane: NE Northeast-Quadrant: SE Southeast-Quadrant: NW Northwest-Quadrant: ZW Southwest-Quadrant: Cost differences were adjusted for age, gender, body mass index (BMI), and severity of back and leg pain at baseline
  3. 1adjusted for baseline utility values, work status, age, gender
  4. 2adjusted for baseline values, level of herniated disc
  5. 3adjusted for baseline values, age, gender, body mass index (BMI), and severity of back and leg pain at baseline. Lasègue’s sign
  6. 4adjusted for baseline values, work status, gender
  7. 5percentage point (difference in percentage recovered between intervention -and control group) adjusted for work status
  8. 6No patients were recovered, cannot be estimated
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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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