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Table 4 Preoperative and postoperative coagulation and fibrinolysis indicators in trauma patients

From: The efficacy and safety of different does of intravenous tranexamic acid on blood loss in fresh foot and ankle fractures: a prospective, randomized controlled study

Variable

PC(30)

LD(30)

MD(30)

HD(30)

UD(30)

P *

PT (s)

d0

11.77 ± 1.50

11.34 ± 0.48

11.24 ± 0.54

11.50 ± 0.60

11.77 ± 0.85

0.601

d3

11.87 ± 1.86

11.52 ± 0.22

11.79 ± 0.18

11.59 ± 0.24

11.66 ± 0.32

0.513

D1

12.53 ± 2.06

11.77 ± 0.20

12.41 ± 0.18

12.18 ± 0.57

12.13 ± 0.43

0.072

D3

11.66 ± 2.38

11.62 ± 0.20

11.66 ± 0.58

11.54 ± 0.65

11.47 ± 0.21

0.965

INR

d0

0.98 ± 0.06

0.98 ± 0.04

0.96 ± 0.03

0.99 ± 0.05

0.99 ± 0.06

0.617

d3

1.00 ± 0.31

0.99 ± 0.02

1.01 ± 0.01

0.98 ± 0.02

0.99 ± 0.03

0.948

D1

1.04 ± 0.30

1.04 ± 0.03

1.07 ± 0.01

1.05 ± 0.05

1.05 ± 0.03

0.892

D3

0.97 ± 0.14

0.99 ± 0.02

0.99 ± 0.05

0.99 ± 0.06

0.97 ± 0.02

0.441

FIB (g/L)

d0

3.4 ± 0.45

3.25 ± 0.61

3.36 ± 0.66

3.28 ± 0.62

3.29 ± 1.01

0.923

d3

4.42 ± 1.19

4.14 ± 0.70

3.75 ± 0.42

3.41 ± 1.42

3.41 ± 0.56

<0.001

D0

3.51 ± 0.37

3.50 ± 0.64

3.49 ± 0.57

3.49 ± 1.08

3.51 ± 0.55

0.982

D1

4.89 ± 1.60

4.58 ± 0.61

4.18 ± 1.03

3.75 ± 1.15

3.56 ± 0.80

<0.001

D3

5.98 ± 2.13

5.25 ± 1.02

5.13 ± 0.88

4.71 ± 1.19

4.51 ± 1.01

<0.001

D-dimer (ug/ml)

d0

0.43 ± 0.19

0.48 ± 0.26

0.46 ± 0.14

0.37 ± 0.21

0.42 ± 0.19

0.293

d3

1.13 ± 0.57

1.03 ± 0.79

0.94 ± 0.28

0.99 ± 0.25

0.72 ± 0.26

<0.001

D0

0.70 ± 0.39

0.69 ± 0.37

0.68 ± 0.23

0.68 ± 0.20

0.69 ± 0.15

0.996

D1

3.97 ± 2.77

4.15 ± 2.99

3.34 ± 3.19

2.44 ± 1.83

2.02 ± 1.37

<0.001

D3

2.03 ± 1.32

1.50 ± 0.75

1.11 ± 0.69

0.82 ± 0.68

0.75 ± 0.40

<0.001

  1. Abbreviation: PT, prothrombin time; INR, international normalized ratio; D-dimer, D-dimer; FIB, fibrin (ogen)
  2. * One-way analysis of variance;