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  1. Medial tibial stress syndrome is one of the most common causes of exertional leg pain in runners whereas musculoskeletal tumors and tumor-like lesions are rare encounters in orthopedic sports medicine practice.

    Authors: Andreas Toepfer, Norbert Harrasser, Ulrich Lenze, Franz Liska, Heinrich Mühlhofer, Rüdiger von Eisenhart-Rothe and Ingo J. Banke
    Citation: BMC Musculoskeletal Disorders 2015 16:220
  2. The purpose of this study was to investigate the prevalence of four types of chronic pain (headache, abdominal pain, neck and shoulder pain (NSP), and low back pain (LBP)) and to explore the relationship betwe...

    Authors: Yongxing Zhang, Guoying Deng, Zhiqing Zhang, Qian Zhou, Xiang Gao, Liqing Di, Qianzi Che, Xiaoyu Du, Yun Cai, Xuedong Han and Qinghua Zhao
    Citation: BMC Musculoskeletal Disorders 2015 16:219
  3. Osteoarthritis (OA) is a multifactorial degenerative condition of the whole joint with a complex pathogenesis whose development and progression is significantly mediated by interactions between the joint carti...

    Authors: Javier Fernández-Torres, Cristina Hernández-Díaz, Rolando Espinosa-Morales, Javier Camacho-Galindo, Norma del Carmen Galindo-Sevilla, Ámbar López-Macay, Yessica Zamudio-Cuevas, Karina Martínez-Flores, Mónica Guadalupe Santamaría-Olmedo, Carlos Pineda, Julio Granados, Gabriela Angélica Martínez-Nava, Marwin Gutiérrez and Alberto G. López-Reyes
    Citation: BMC Musculoskeletal Disorders 2015 16:218
  4. The goal of this present study was to precisely determine the dimension and location of the impaction fracture on the lateral femoral condyle in patients with an ACL rupture.

    Authors: Thomas Hoffelner, Isabel Pichler, Philipp Moroder, Michael Osti, Martin Hudelmaier, Wolfgang Wirth, Herbert Resch and Alexander Auffarth
    Citation: BMC Musculoskeletal Disorders 2015 16:217
  5. The purpose of our retrospective study was to evaluate the preliminary result of distraction osteogenesis in patient with tibial shortening after initial union of Congenital Pseudarthrosis of the Tibia (CPT).

    Authors: Guang-hui Zhu, Hai-bo Mei, Rong-guo He, Kun Liu, Jin Tang and Jiang-yan Wu
    Citation: BMC Musculoskeletal Disorders 2015 16:216
  6. Osteoarthritis (OA) is one of the most common joint diseases in elderly people, however, the underlying mechanism of OA pathogenesis is not completely clear. Periostin, the extracellular protein, has been show...

    Authors: Ryota Chijimatsu, Yasuo Kunugiza, Yoshiaki Taniyama, Norimasa Nakamura, Tetsuya Tomita and Hideki Yoshikawa
    Citation: BMC Musculoskeletal Disorders 2015 16:215
  7. Rheumatoid Arthritis is a progressive and disabling disease, predicted to increase in prevalence over the next 50 years. Self-management is acknowledged as an integral part in the management of chronic disease...

    Authors: Vironique Vermaak, N. Kathy Briffa, Bob Langlands, Charles Inderjeeth and Jean McQuade
    Citation: BMC Musculoskeletal Disorders 2015 16:214
  8. The importance of pelvic incidence-lumbar lordosis (PI-LL: PI minus LL) mismatch is emphasized in long-segment fusion for adult spinal deformity; however, there are few studies evaluating the influence of PI-L...

    Authors: Yasuchika Aoki, Arata Nakajima, Hiroshi Takahashi, Masato Sonobe, Fumiaki Terajima, Masahiko Saito, Kazuhisa Takahashi, Seiji Ohtori, Atsuya Watanabe, Takayuki Nakajima, Makoto Takazawa, Sumihisa Orita, Yawara Eguchi and Koichi Nakagawa
    Citation: BMC Musculoskeletal Disorders 2015 16:213
  9. The recent discovery of residing tendon stem/progenitor cells has triggered a growing interest in stem cells as a useful tool in tendon repair. Our knowledge of their involvement in naturally healing tendons i...

    Authors: Eva Runesson, Paul Ackermann, Jón Karlsson and Bengt I Eriksson
    Citation: BMC Musculoskeletal Disorders 2015 16:212
  10. Fifth metatarsal (MT-V) stress fractures often exhibit delayed union and are high-risk fractures for non-union. Surgical treatment, currently considered as the gold standard, does not give optimal results, wit...

    Authors: Hanneke Weel, Wouter H. Mallee, C. Niek van Dijk, Leendert Blankevoort, Simon Goedegebuure, J. Carel Goslings, John G. Kennedy and Gino M. M. J. Kerkhoffs
    Citation: BMC Musculoskeletal Disorders 2015 16:211
  11. Osteoporotic fractures are associated with mortality in postmenopausal woman. Whether raloxifen treatment after vertebroplasty can reduce mortality is unclear in this group. To compare the effect of raloxifene...

    Authors: Fu-Mei Su, Ying-Chou Chen, Tien-Tsai Cheng, Wei-Che Lin and Chun-Chung Lui
    Citation: BMC Musculoskeletal Disorders 2015 16:209
  12. The unilateral approach for bilateral decompression was developed as an alternative to laminectomy. Unilateral laminotomy has been rated technically considerably more demanding and associated with more periope...

    Authors: Yi-Hung Ho, Yuan-Kun Tu, Chih-Kun Hsiao and Chih-Han Chang
    Citation: BMC Musculoskeletal Disorders 2015 16:208
  13. The use of an interbody fusion device (cage) to assist fusion and increase intervertebral stability is widely supported. We applied the morselized impacted bone graft method without using a cage in a single le...

    Authors: Chaoliang Lv, Xianzhou Li, Haicheng Zhang, Junrong Lv and Hongmei Zhang
    Citation: BMC Musculoskeletal Disorders 2015 16:207
  14. Thoracic ossification of ligamentum flavum (TOLF) is a progressively disabling disease. Isolated or continuous TOLF has been frequently reported in literature, however there are very few reports of multilevel ...

    Authors: Wen-jing Li, Shi-gong Guo, Zhi-jian Sun and Yu Zhao
    Citation: BMC Musculoskeletal Disorders 2015 16:206
  15. No previous studies have created and validated prediction models for outcomes in patients receiving spinal manipulation for care of chronic low back pain (cLBP). We therefore conducted a secondary analysis alo...

    Authors: Darcy Vavrek, Mitchell Haas, Moni Blazej Neradilek and Nayak Polissar
    Citation: BMC Musculoskeletal Disorders 2015 16:205
  16. Traditionally, non-communicable diseases including musculoskeletal disorders have not been a priority in low-and-middle income countries. The main aim of this paper is to assess age and gender specific burden ...

    Authors: Emmanuel Kweku Nakua, Easmon Otupiri, Veronica Millicent Dzomeku, Ellis Owusu-Dabo, Peter Agyei-Baffour, Alfred Edwin Yawson, Gloria Folson and Sandra Hewlett
    Citation: BMC Musculoskeletal Disorders 2015 16:204
  17. Activation of the deep stabilizing trunk muscle transversus abdominis (TrA) is important for trunk stabilization and spine stability. Sling exercises are used for the activation of trunk muscles, therefore we ...

    Authors: Jörn Lükens, Kim J. Boström, Christian Puta, Tobias L. Schulte and Heiko Wagner
    Citation: BMC Musculoskeletal Disorders 2015 16:203
  18. Previous studies have found inflammation, growth factors, and androgen signaling pathways all contribute to sarcopenia. However, few studies simultaneously have investigated the association between these poten...

    Authors: Yongxia Meng, Hongmei Wu, Yi Yang, Huanmin Du, Yang Xia, Xiaoyan Guo, Xing Liu, Chunlei Li and Kaijun Niu
    Citation: BMC Musculoskeletal Disorders 2015 16:202
  19. Stratification strategies based on identifying patient’s prognosis in order to guide patient care constitute one of the most prominent and recent approach in low back pain research. The STarT Back Screening To...

    Authors: Isabelle Pagé, Jacques Abboud, Julie O᾽Shaughnessy, Louis Laurencelle and Martin Descarreaux
    Citation: BMC Musculoskeletal Disorders 2015 16:201
  20. Bone tunnel enlargement is a phenomenon present in all anterior cruciate ligament (ACL)- reconstruction techniques. It was hypothesized that press-fit fixation using a free autograft bone plug reduces the over...

    Authors: Ralph Akoto, Jonas Müller-Hübenthal, Maurice Balke, Malte Albers, Bertil Bouillon, Philip Helm, Marc Banerjee and Jürgen Höher
    Citation: BMC Musculoskeletal Disorders 2015 16:200
  21. This study compared the rates of mortality, medical complication, and reoperation after fixation surgery for displaced femoral neck fracture with those after hemiarthroplasty surgery for undisplaced femoral ne...

    Authors: Jeff Chien-Fu Lin and Wen-Miin Liang
    Citation: BMC Musculoskeletal Disorders 2015 16:199
  22. Flight-related neck/shoulder pain is frequent among military helicopter pilots and crew members. With a lifetime prevalence of 81 % for pilots and 84 % for crew members, the prevalence of neck pain is consider...

    Authors: Mike Murray, Britt Lange, Bo Riebeling Nørnberg, Karen Søgaard and Gisela Sjøgaard
    Citation: BMC Musculoskeletal Disorders 2015 16:198
  23. The treatment of end-stage tuberculosis (TB) of the knee remains a significant clinical challenge, and clinical data are lacking. This study aimed to retrospectively determine the outcome of single-stage knee ...

    Authors: Xin Tang, Jing Zhu, Qi Li, Gang Chen, Weili Fu and Jian Li
    Citation: BMC Musculoskeletal Disorders 2015 16:197
  24. Gout is a consequence of an innate immune reaction to monosodium urate crystals deposited in joints. Acute gout attacks can be triggered by dietary factors that are themselves associated with serum urate level...

    Authors: Tanya J Flynn, Murray Cadzow, Nicola Dalbeth, Peter B Jones, Lisa K Stamp, Jennie Harré Hindmarsh, Alwyn S Todd, Robert J Walker, Ruth Topless and Tony R Merriman
    Citation: BMC Musculoskeletal Disorders 2015 16:196
  25. Sensorimotor function is degraded in patients after lower limb arthroplasty. Sensorimotor training is thought to improve sensorimotor skills, however, the optimal training stimulus with regard to volume, frequ...

    Authors: Torsten Pohl, Torsten Brauner, Scott Wearing, Knut Stamer and Thomas Horstmann
    Citation: BMC Musculoskeletal Disorders 2015 16:195
  26. Although women with rheumatoid arthritis (RA) face a number of challenges in negotiating the journey to parenthood, no studies have explored the information needs of women with RA in relation to their childbea...

    Authors: Ilana N. Ackerman, Joanne E. Jordan, Sharon Van Doornum, Margaret Ricardo and Andrew M. Briggs
    Citation: BMC Musculoskeletal Disorders 2015 16:194
  27. Osteoarthritis is one of the primary causes of long-term functional disability. With an estimated 13.5 % prevalence in the general population contributes to a significant financial burden both for patients and...

    Authors: Despena Andrioti, Kypros Kyprianou and George Charalambous
    Citation: BMC Musculoskeletal Disorders 2015 16:193
  28. Bone resorption in the proximal femur due to stress shielding has been observed in a number of conventional cementless implants used in total hip arthroplasty. Short femoral-neck implants are claiming less int...

    Authors: Wolfram Steens, Friedrich Boettner, Rainer Bader, Ralf Skripitz and Alberto Schneeberger
    Citation: BMC Musculoskeletal Disorders 2015 16:192
  29. Endothelial damage and activation may play central roles in the pathogenesis of systemic sclerosis (SSc) and are reflected by microparticles (MPs) and soluble selectins. The objective of this study was to dete...

    Authors: Line V. Iversen, Susanne Ullman, Ole Østergaard, Christoffer T. Nielsen, Poul Halberg, Tonny Karlsmark, Niels H.H. Heegaard and Søren Jacobsen
    Citation: BMC Musculoskeletal Disorders 2015 16:191
  30. Periodontitis (PD) has been reported to be associated with rheumatoid arthritis (RA). Porphyromonas gingivalis (P. gingivalis) is a gram-negative anaerobic bacterium that is recognized as one of the major pathoge...

    Authors: Joo Youn Lee, In Ah Choi, Jin-Hee Kim, Kyoung-Hwa Kim, Eun Young Lee, Eun Bong Lee, Yong-Moo Lee and Yeong Wook Song
    Citation: BMC Musculoskeletal Disorders 2015 16:190
  31. Rotator cuff repair incidence rates have reportedly increased in the United States and England. Here we analyzed nationwide data relating to rotator cuff repairs recorded in the Finnish National Hospital Disch...

    Authors: Juha Paloneva, Vesa Lepola, Ville Äärimaa, Antti Joukainen, Jari Ylinen and Ville M Mattila
    Citation: BMC Musculoskeletal Disorders 2015 16:189
  32. Systemic lupus erythematosus (SLE) is an autoimmune multi-organ disease, characterized by episodes of disease flares and remissions over time, which may restrain affected patients’ ability to perform daily act...

    Authors: Mathilda Björk, Örjan Dahlström, Jonas Wetterö and Christopher Sjöwall
    Citation: BMC Musculoskeletal Disorders 2015 16:188
  33. The assessment of mobility is important in the acute care setting. Existing tests suffer from limitations. The aim of the study was to examine the inter-rater reliability, the validity, the sensitivity to chan...

    Authors: Karin Pieber, Malvina Herceg, Tatjana Paternostro-Sluga, Eleonore Pablik, Michael Quittan, Peter Nicolakis, Veronika Fialka-Moser and Richard Crevenna
    Citation: BMC Musculoskeletal Disorders 2015 16:187
  34. There are quite a few controversies on the surgical management of single-segment thoracic spinal tuberculosis with neurological deficits (STSTND). In this study, the clinical efficacy and feasibility of one-st...

    Authors: Hao Zeng, Penghui Zhang, Xiongjie Shen, Chengke Luo, Zhengquan Xu, Yupeng Zhang, Zheng Liu and Xiyang Wang
    Citation: BMC Musculoskeletal Disorders 2015 16:186
  35. Exercise therapy following total hip replacement (THR) is considered to be important during the initial postoperative care, but till date only a few evidence-based recommendations exist. The aim of this survey...

    Authors: Christine Eulenburg, Anna-Lina Rahlf, Andrej Kutasow and Astrid Zech
    Citation: BMC Musculoskeletal Disorders 2015 16:185
  36. Patellar tendinopathy identified by imaging modalities has been reported in asymptomatic athletes and associated with tendon-related symptoms. However there is little data in community-based populations. The a...

    Authors: Jason Toppi, Jessica Fairley, Flavia M. Cicuttini, Jill Cook, Susan R. Davis, Robin J. Bell, Fahad Hanna and Yuanyuan Wang
    Citation: BMC Musculoskeletal Disorders 2015 16:184
  37. Vitamin D deficiency has been associated with a high number of health outcomes, and its role on the immune system has been deeply investigated in recent years, although poor data are still available on vitamin...

    Authors: Valentina Signori, Carlo L. Romanò, Elena De Vecchi, Roberto Mattina and Lorenzo Drago
    Citation: BMC Musculoskeletal Disorders 2015 16:183
  38. The aim of this study was to evaluate, the existence of a signature of differentially expressed microRNAs (miRNAs) during osteogenic differentiation of bone marrow MSCs from OA and healthy donors and to descri...

    Authors: Pilar Tornero-Esteban, Luis Rodríguez-Rodríguez, Lydia Abásolo, María Tomé, Pedro López-Romero, Eva Herranz, Manuel A. González, Fernando Marco, Enrique Moro, Benjamín Fernández-Gutiérrez and José Ramón Lamas
    Citation: BMC Musculoskeletal Disorders 2015 16:182
  39. Minimal invasive surgery (MIS) has gained growing popularity in total hip arthroplasty (THA) but concerns exist regarding component malpositioning. The aim of the present study was to evaluate femoral and acet...

    Authors: Moritz M. Innmann, Marcus R. Streit, Jeanette Kolb, Jochen Heiland, Dominik Parsch, Peter R. Aldinger, Matthias Königshausen, Tobias Gotterbarm and Christian Merle
    Citation: BMC Musculoskeletal Disorders 2015 16:180
  40. Core myopathies are a clinically and genetically heterogeneous group of congenital myopathies with the common defined histopathological feature of focally reduced oxidative activity on muscle biopsy. It has a ...

    Authors: Rafael de Paiva Luciano, Eduardo Barros Puertas, Delio Eulalio Martins, Flavio Faloppa, David Del Curto, Luciano Miller Reis Rodrigues, Beny Schmidt, Acary Souza Bulle de Oliveira and Marcelo Wajchenberg
    Citation: BMC Musculoskeletal Disorders 2015 16:179
  41. Osteoarthritis (OA) is likely to become an increasing burden in the coming decades. Various agents have been developed to slow the progression of OA, and are collectively known as ‘disease-modifying drugs’, ho...

    Authors: Kai Huang, Jia-peng Bao, Gavin James Jennings and Li-dong Wu
    Citation: BMC Musculoskeletal Disorders 2015 16:178
  42. Unicondylar knee arthroplasty (UKA) is a well-established treatment for isolated osteoarthritis (OA) of the medial knee compartment. Aim of this retrospective study was to evaluate the early clinical and radio...

    Authors: Joel Baur, Lukas Zwicky, Michael Tobias Hirschmann, Thomas Ilchmann and Martin Clauss
    Citation: BMC Musculoskeletal Disorders 2015 16:177
  43. The emergence of new therapies for the treatment of rheumatoid arthritis (RA), the paucity of head-to-head studies, and the heterogeneous nature of responses to current biologics highlight the need for the ide...

    Authors: Hubert G. Nüßlein, Rieke Alten, Mauro Galeazzi, Hanns-Martin Lorenz, Michael T. Nurmohamed, William G. Bensen, Gerd R. Burmester, Hans-Hartmut Peter, Karel Pavelka, Melanie Chartier, Coralie Poncet, Christiane Rauch and Manuela Le Bars
    Citation: BMC Musculoskeletal Disorders 2015 16:176
  44. Fixation failure is a relatively common sequela of surgical management of proximal humerus fractures (PHF). The purpose of this study is to understand the current state of the literature with regard to the bio...

    Authors: David Cruickshank, Kelly A. Lefaivre, Herman Johal, Norma J. MacIntyre, Sheila A. Sprague, Taryn Scott, Pierre Guy, Peter A. Cripton, Michael McKee, Mohit Bhandari and Gerard P. Slobogean
    Citation: BMC Musculoskeletal Disorders 2015 16:175
  45. The Timed Up and Go (TUG) test is quick and easy tests to assess patients’ functional mobility. However, its reliability in individuals with knee osteoarthritis (OA) has not been well established. The aims of ...

    Authors: Ahmad Alghadir, Shahnawaz Anwer and Jean-Michel Brismée
    Citation: BMC Musculoskeletal Disorders 2015 16:174
  46. Retrieved metal-on-metal acetabular cups are valuable resources in investigating the wear behaviour of failed hip implants, but adequate methods to do so are lacking. To further contribute to addressing this i...

    Authors: Garima Govind, Johann Henckel, Harry Hothi, Shiraz Sabah, John Skinner and Alister Hart
    Citation: BMC Musculoskeletal Disorders 2015 16:173
  47. The purpose was to investigate prevalence of bilateral discoid lateral menisci (DLM) in Han Chinese patients who received surgery for symptomatic DLM, as well as a follow-up study of their asymptomatic contral...

    Authors: Wen-Xin Liu, Jin-Zhong Zhao, Xiao-Qiao Huangfu, Yao-Hua He and Xing-Guang Yang
    Citation: BMC Musculoskeletal Disorders 2015 16:172
  48. Acceptance and Commitment Therapy (ACT) for pain offers an alternative to traditional Cognitive Behavioural Therapy (CBT) approaches. ACT focuses on the enhancement of ‘psychological flexibility’ that enables ...

    Authors: Antonia Barke, Jenny Riecke, Winfried Rief and Julia A. Glombiewski
    Citation: BMC Musculoskeletal Disorders 2015 16:171

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