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  1. Chronic non-specific low back pain is a major socioeconomic public health issue worldwide and, despite the volume of research in the area, it is still a difficult-to-treat condition. The conservative analgesic...

    Authors: Fuad Ahmad Hazime, Diego Galace de Freitas, Renan Lima Monteiro, Rafaela Lasso Maretto, Nilza Aparecida de Almeida Carvalho, Renata Hydee Hasue and Silvia Maria Amado João
    Citation: BMC Musculoskeletal Disorders 2015 16:7
  2. The application of radiofrequency energy (RFE) has become widespread for surgical performed chondroplasty especially due to the anticipated sealing effect, however the safety of this procedure in the wrist rem...

    Authors: Michaela Huber, Christoph Eder, Markus Loibl, Arne Berner, Johannes Zellner, Richard Kujat, Michael Nerlich and Sebastian Gehmert
    Citation: BMC Musculoskeletal Disorders 2015 16:6
  3. Recently, analysis of bone from knockout mice identified muscarinic acetylcholine receptor subtype M3 (mAChR M3) and nicotinic acetylcholine receptor (nAChR) subunit α2 as positive regulator of bone mass accru...

    Authors: Katrin S Lips, Özcan Yanko, Mathias Kneffel, Imke Panzer, Vivien Kauschke, Maria Madzharova, Anja Henss, Peter Schmitz, Marcus Rohnke, Tobias Bäuerle, Yifei Liu, Marian Kampschulte, Alexander C Langheinrich, Lutz Dürselen, Anita Ignatius, Christian Heiss…
    Citation: BMC Musculoskeletal Disorders 2015 16:5
  4. Wrist movements become impaired with disease progression in various neuromuscular disorders. With the development of new therapies, thorough measurement of muscle strength is crucial to document natural diseas...

    Authors: Valérie Decostre, Aurélie Canal, Gwenn Ollivier, Isabelle Ledoux, Amélie Moraux, Valérie Doppler, Christine Anne Mary Payan and Jean-Yves Hogrel
    Citation: BMC Musculoskeletal Disorders 2015 16:4
  5. To compare the clinical and radiological features of intra-/juxta-articular osteoid osteoma and extra-articular osteoid osteoma in skeletally immature patients, paying special attention to the skeletal complic...

    Authors: Mi Hyun Song, Won Joon Yoo, Tae-Joon Cho, Chin Youb Chung, Moon Seok Park, Jung-Eun Cheon and In Ho Choi
    Citation: BMC Musculoskeletal Disorders 2015 16:3
  6. Melorheostosis is quite a rare bone disease with still unclear ethiology. Although multifocal affection is highly debilitating with unfavorable prognosis, there is no clear consensus about therapeutical approa...

    Authors: Vaclav Vyskocil, Karel Koudela Jr, Tomas Pavelka, Kristyna Stajdlova and David Suchy
    Citation: BMC Musculoskeletal Disorders 2015 16:2
  7. We tried to compare the functional and psychosocial outcomes after various reconstruction methods according to tumor location following resection of osteosarcoma in distal femur.

    Authors: SongFeng Xu, XiuChun Yu, Ming Xu, ZhiHou Fu, Yu Chen, YuXi Sun and Qing Su
    Citation: BMC Musculoskeletal Disorders 2014 15:453
  8. Rheumatoid Arthritis (RA) is one of the most common autoimmune diseases, affecting approximately 1% of the UK adult population. Patients suffer considerable pain, stiffness and swelling and can sustain various...

    Authors: Nuria C Navarro Coy, Sarah Brown, Ailsa Bosworth, Claire T Davies, Paul Emery, Colin C Everett, Catherine Fernandez, Janine C Gray, Suzanne Hartley, Claire Hulme, Anne-Maree Keenan, Christopher McCabe, Anthony Redmond, Catherine Reynolds, David Scott, Linda D Sharples…
    Citation: BMC Musculoskeletal Disorders 2014 15:452
  9. Knee osteoarthritis affects 10% of the UK population over 55 years, resulting in pain and decreased quality of life. Knee replacement surgery has a proven benefit, with over 85,000 performed each year in the U...

    Authors: Tim Barlow, Mark Dunbar, Andrew Sprowson, Nick Parsons and Damian Griffin
    Citation: BMC Musculoskeletal Disorders 2014 15:451
  10. To investigate the risk of hepatitis B virus (HBV) reactivation in rheumatoid arthritis (RA) patients with HBV carrier state during treatment of disease-modifying antirheumatic drugs (DMARDs) and the use of an...

    Authors: Ying-Qian Mo, An-Qi Liang, Jian-Da Ma, Le-Feng Chen, Dong-Hui Zheng, H Ralph Schumacher and Lie Dai
    Citation: BMC Musculoskeletal Disorders 2014 15:449
  11. The aim of present meta-analysis was to evaluate the effectiveness of tranexamic acid (TXA) use in reducing blood loss and the related thrombotic complications in spinal surgery.

    Authors: Fan Zhang, Kun Wang, Feng-Ning Li, Xuan Huang, Quan Li, Zhi Chen, Yi-Bo Tang, Hong-Xing Shen and Qing-Xin Song
    Citation: BMC Musculoskeletal Disorders 2014 15:448
  12. Longitudinal assessment of bone marrow lesions (BMLs) in knee osteoarthritis (KOA) by MRI is usually performed using semi-quantitative grading methods. Quantitative segmentation methods may be more sensitive t...

    Authors: Flemming K Nielsen, Niels Egund, David Peters and Anne Grethe Jurik
    Citation: BMC Musculoskeletal Disorders 2014 15:447
  13. The objective of this study was to identify leukocyte cell types found within the synovia of patients with seronegative spondylarthropathies (SpA), such as ankylosing spondylitis (AS), using transcription base...

    Authors: Robin M Hallett and Tracy Chew
    Citation: BMC Musculoskeletal Disorders 2014 15:446
  14. People with rheumatoid arthritis are at greater risk of morbidity and mortality from cardiovascular disease than the general population. Sustained physical activity increases cardio-respiratory fitness and red...

    Authors: Peter C Rouse, Jet JCS Veldhuijzen Van Zanten, George S Metsios, Nikos Ntoumanis, Chen-an Yu, Yiannis Koutedakis, Sally AM Fenton, Joanna Coast, Hema Mistry, George D Kitas and Joan L Duda
    Citation: BMC Musculoskeletal Disorders 2014 15:445
  15. Among laboratory technicians, the prevalence of neck and shoulder pain is widespread possibly due to typical daily work tasks such as pipetting, preparing vial samples for analysis, and data processing on a co...

    Authors: Kenneth Jay, Mikkel Brandt, Emil Sundstrup, MC schraefel, Markus D Jakobsen, Gisela Sjøgaard and Lars L Andersen
    Citation: BMC Musculoskeletal Disorders 2014 15:444
  16. Percutaneous pedicle screw instrumentation is a minimally invasive surgical technique; however, the effects of using percutaneous pedicle screw fixation in treating patients with spinal infections have not yet...

    Authors: Tung-Yi Lin, Tsung-Ting Tsai, Meng-Ling Lu, Chi-Chien Niu, Ming-Kai Hsieh, Tsai-Sheng Fu, Po-Liang Lai, Lih-Huei Chen and Wen-Jer Chen
    Citation: BMC Musculoskeletal Disorders 2014 15:443
  17. Obesity is a well-known risk factor for osteoarthritis (OA). The majority of obesity research in OA is performed using self-reported BMI-data, however, its validity in persons with OA is unknown. The aim of th...

    Authors: Karin Magnusson, Ida K Haugen, Nina Østerås, Lars Nordsletten, Bård Natvig and Kåre Birger Hagen
    Citation: BMC Musculoskeletal Disorders 2014 15:442
  18. Few, if any data are available are available regarding the time-trends in characteristics of patients who have undergone primary THA. Our objective was to examine the time-trends in key demographic and clinica...

    Authors: Jasvinder A Singh and David G Lewallen
    Citation: BMC Musculoskeletal Disorders 2014 15:441
  19. Shoulder instability is a common problem affecting young adults. Stabilization surgery followed by physiotherapy rehabilitation has been shown to reduce the chance of further episodes of shoulder dislocation a...

    Authors: Anju Jaggi, Susan Alexander, Robert Herbert, Lennard Funk and Karen A Ginn
    Citation: BMC Musculoskeletal Disorders 2014 15:439
  20. The aim of our meta-analysis is to understand the relationship between the pathogenesis of osteoarthritis and the expression levels of vascular endothelial growth factor (VEGF) in multiple disease tissues in o...

    Authors: Quan Yuan, Li Sun, Jian-Jun Li and Chun-Hou An
    Citation: BMC Musculoskeletal Disorders 2014 15:437
  21. Lateral ankle sprain (LAS) has often been considered an injury leading to localized joint impairments affecting the musculoskeletal system. Persistent chronic ankle instability and bilateral alterations in mot...

    Authors: Maude Bastien, Hélène Moffet, Laurent J Bouyer, Marc Perron, Luc J Hébert and Jean Leblond
    Citation: BMC Musculoskeletal Disorders 2014 15:436
  22. The main goals of the standard treatment for advanced symptomatic knee osteoarthritis, total knee arthroplasty (TKA), are pain reduction and restoration of knee motion.

    Authors: Matthias Christen, Emin Aghayev and Bernhard Christen
    Citation: BMC Musculoskeletal Disorders 2014 15:435
  23. Although minimally invasive approaches are widely used in many areas of orthopedic surgery nonunion therapy remains a domain of open surgery. Some attempts have been made to introduce minimally invasive proced...

    Authors: Thorsten Tjardes, Michael Roland, Robin Otchwemah, Tim Dahmen, Stefan Diebels and Bertil Bouillon
    Citation: BMC Musculoskeletal Disorders 2014 15:434
  24. The prosthesis of contemporary total knee arthroplasty (TKA) has been modified to provide a more familiar environment for higher flexion angle of the replaced knee. The design modifications continue based on e...

    Authors: Jai Gon Seo, Young-Wan Moon, Moon Jong Chang, Byung Chul Jo, Yong Beom Park, Deuk Soo Lim and Byung Hoon Lee
    Citation: BMC Musculoskeletal Disorders 2014 15:433
  25. The Swedish National Patient Register offers unique possibilities for identification of large cohorts, such as patients with rheumatoid arthritis (RA). Although the overall diagnostic validity in the register ...

    Authors: Kristin Waldenlind, Jonas K Eriksson, Bernhard Grewin and Johan Askling
    Citation: BMC Musculoskeletal Disorders 2014 15:432
  26. Cartilage is an avascular and aneural tissue. Chondrocytes thrive in this restricted environment of low oxygen tension and poor nutrient availability which has led to suggestions that hypoxia may be a protecti...

    Authors: Karl Alvarez, María C de Andrés, Atsushi Takahashi and Richard O C Oreffo
    Citation: BMC Musculoskeletal Disorders 2014 15:431
  27. Patients with anterior cruciate ligament (ACL) injury often exhibit reduced movement quality during functional tasks in the form of a knee-medial-to-foot position (KMFP). This movement pattern is suggested to ...

    Authors: Anna Cronström and Eva Ageberg
    Citation: BMC Musculoskeletal Disorders 2014 15:430
  28. Abnormal longitudinal growth has been identified in the early pubertal stage of idiopathic scoliosis (IS) and is thought to contribute to the development of scoliosis. This phenotype may be caused by abnormal ...

    Authors: Xin Zheng, Weijun Wang, Bangping Qian, Shoufeng Wang, Zezhang Zhu, Bin Wang, Xu Sun, Yitao Ding and Yong Qiu
    Citation: BMC Musculoskeletal Disorders 2014 15:429
  29. Joint hypermobility is a common clinical characteristic of patients with Osteogenesis imperfecta (OI), a disorder with serious comorbidities of scoliosis and cranial base anomalies. This study aimed at evaluat...

    Authors: Heidi Arponen, Outi Mäkitie and Janna Waltimo-Sirén
    Citation: BMC Musculoskeletal Disorders 2014 15:428
  30. Written information can be of benefit to both practitioners and patients and the provision of quality information is emphasised as a core intervention by United Kingdom National Institute of Clinical Excellence (...

    Authors: Andrew Morden, Clare Jinks, Bie Nio Ong, Mark Porcheret and Krysia S Dziedzic
    Citation: BMC Musculoskeletal Disorders 2014 15:427
  31. Chondromalacia, lateral patellar compression syndrome and osteoarthritis are common patellofemoral joint disorders leading to functional and/or structural disturbances in articular surfaces. The objective of t...

    Authors: Dawid Bączkowicz and Edyta Majorczyk
    Citation: BMC Musculoskeletal Disorders 2014 15:426
  32. Recent work has shown that the gap junction protein connexin43 (Cx43) is upregulated in cells of the joint during osteoarthritis (OA). Here we examined if the OA-associated increase in Cx43 expression impacts ...

    Authors: Aditi Gupta, Corinne Niger, Atum M Buo, Eric R Eidelman, Richard J Chen and Joseph P Stains
    Citation: BMC Musculoskeletal Disorders 2014 15:425
  33. Expandable screws have greater pullout strength than conventional screws. The purpose of this study was to compare the biomechanical stability provided by a new built-in expandable anterior spinal fixation sys...

    Authors: Chu-Song Zhou, Yan-Fang Xu, Yu Zhang, Zhong Chen and Hai Lv
    Citation: BMC Musculoskeletal Disorders 2014 15:424
  34. Subjective symptoms of temporomandibular disorders (TMDs) have rarely been studied by age group. We aimed to compare self-reported pain intensity, sleeping difficulty, and treatment outcomes of patients with m...

    Authors: Hiroyuki Karibe, Greg Goddard, Kisaki Shimazu, Yuichi Kato, Sachie Warita-Naoi and Tomomi Kawakami
    Citation: BMC Musculoskeletal Disorders 2014 15:423
  35. Notochordal cells (NC) remain in the focus of research for regenerative therapy for the degenerated intervertebral disc (IVD) due to their progenitor status. Recent findings suggested their regenerative action...

    Authors: Benjamin Gantenbein, Elena Calandriello, Karin Wuertz-Kozak, Lorin M Benneker, Marius JB Keel and Samantha CW Chan
    Citation: BMC Musculoskeletal Disorders 2014 15:422
  36. Sternoclavicular joint (SCJ) arthropathy is an uncommon cause of mechanical pain. The aim of this study is to evaluate the diagnostic value of two active clinical tests for localizing the sternoclavicular join...

    Authors: Alexander Van Tongel, Anne Karelse, Bart Berghs, Tom Van Isacker and Lieven De Wilde
    Citation: BMC Musculoskeletal Disorders 2014 15:421
  37. Chronic low back pain is one of the four most common diseases in the world with great socioeconomic impact. Supervised exercise therapy is one of the treatments suggested for this condition; however, the recom...

    Authors: Yuri Rafael dos Santos Franco, Richard Eloin Liebano, Katherinne Ferro Moura, Naiane Teixeira Bastos de Oliveira, Gisela Cristiane Miyamoto, Matheus Oliveira Santos and Cristina Maria Nunes Cabral
    Citation: BMC Musculoskeletal Disorders 2014 15:420
  38. Neck pain is a common musculoskeletal complaint and is often associated with shoulder or arm pain. There is a paucity of information on effective treatment for neck and arm pain, such as radiculopathy or cervi...

    Authors: Cato A Basson, Aimee Stewart and Witness Mudzi
    Citation: BMC Musculoskeletal Disorders 2014 15:419
  39. Primary care pharmacological management of new musculoskeletal conditions is not consistent, despite guidelines which recommend prescribing basic analgesics before higher potency medications such as opioids or...

    Authors: Mehluli Ndlovu, John Bedson, Peter W Jones and Kelvin P Jordan
    Citation: BMC Musculoskeletal Disorders 2014 15:418
  40. Use of a baseplate with a smaller diameter in reverse shoulder arthroplasty is increasing, especially in patients with a small glenoid or glenoid wear. However, the effect of a smaller baseplate on stability o...

    Authors: Soo-Won Chae, Soung-Yon Kim, Haea Lee, Joung-Ro Yon, Juneyoung Lee and Seung-Ho Han
    Citation: BMC Musculoskeletal Disorders 2014 15:417
  41. Non-specific low back pain (NSLBP) is a large and costly problem. It has a lifetime prevalence of 80% and results in high levels of healthcare cost. It is a major cause for long term sickness amongst the workf...

    Authors: Benjamin E Smith, Chris Littlewood and Stephen May
    Citation: BMC Musculoskeletal Disorders 2014 15:416
  42. The harvest of iliac crest bone grafts (ICBG) is associated with relevant donor site pain, but may be lowered by the application of lidocaine loaded on biodegradable, hemostatic putty for sustained local analg...

    Authors: Marc Andreas Müller, Arne Mehrkens, Roman Zürcher, Patrick Vavken and Victor Valderrabano
    Citation: BMC Musculoskeletal Disorders 2014 15:415
  43. PA28γ (also known as Ki, REG gamma, PMSE3), a member of the ubiquitin-and ATP-independent proteasome activator family 11S, has been proved to show proteasome-dependent and -independent effects on several prote...

    Authors: Melanie Gruner, Anja Moncsek, Stefan Rödiger, Dagmar Kühnhardt, Eugen Feist and Ralf Stohwasser
    Citation: BMC Musculoskeletal Disorders 2014 15:414
  44. The Patient and PRovider Interventions for Managing Osteoarthritis (OA) in Primary Care (PRIMO) study is one of the first health services trials targeting OA in a multi-site, primary care network. This multi-s...

    Authors: Kelli D Allen, Hayden B Bosworth, Ranee Chatterjee, Cynthia J Coffman, Leonor Corsino, Amy S Jeffreys, Eugene Z Oddone, Catherine Stanwyck, William S Yancy Jr and Rowena J Dolor
    Citation: BMC Musculoskeletal Disorders 2014 15:413
  45. Musculoskeletal pain from the upper extremity and shoulder region is commonly reported by computer users. However, the functional status of central pain mechanisms, i.e., central sensitization and conditioned ...

    Authors: Hong-You Ge, Steffen Vangsgaard, Øyvind Omland, Pascal Madeleine and Lars Arendt-Nielsen
    Citation: BMC Musculoskeletal Disorders 2014 15:412
  46. The persistence of knee pain (KP) and its relationship with occupational factors were investigated in two prospective cohorts of French workers: retirees of the Gazel cohort and workers in the Cosali cohort.

    Authors: Eléonore Herquelot, Julie Bodin, Audrey Petit, Catherine Ha, Annette Leclerc, Marcel Goldberg, Marie Zins, Yves Roquelaure and Alexis Descatha
    Citation: BMC Musculoskeletal Disorders 2014 15:411
  47. “Chevron”-Olecranon osteotomies are commonly used for the approach to intraarticular distal humerus fractures but are often associated with procedure related complications. We studied the triceps reflecting ap...

    Authors: Lukas Daniel Iselin, Tobias Mett, Reto Babst, Marcel Jakob and Daniel Rikli
    Citation: BMC Musculoskeletal Disorders 2014 15:406

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